Published by Elsevier Inc. Pityriasis rosea. 8600 Rockville Pike Bookshelf In addition to a corticosteroid cream, New York City-based dermatologist Macrene Alexiades recommends keeping showers short and lukewarm, as "water, sweat, and soap reportedly irritate and inflame the lesions. Ehsani AH, Nasimi M, Bigdelo Z. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection. Marzano AV, Cassano N, Genovese G, Moltrasio C, Vena GA. Cutaneous manifestations in patients with COVID19: a preliminary review of an emerging issue. The typical distribution of the rash is on the trunk between the neck and the knees.". Temiz SA, Abdelmaksoud A, Dursun R, Durmaz K, Sadoughifar R, Hasan A. J Cosmet Dermatol. Interventions: Drago F, Ciccarese G, Rebora A, et al. (2016) 30:5445. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. In some cases, central hyperpigmentation was identified. *Correspondence: Poonkiat Suchonwanit, poonkiat@hotmail.com, ORCID: Kanchana Leerunyakul orcid.org/0000-0002-0669-5611Kallapan Pakornphadungsit orcid.org/0000-0003-4783-0282Poonkiat Suchonwanit orcid.org/0000-0001-9723-0563, COVID-19 Associated Cutaneous Manifestations and COVID-19 Vaccine Related Skin Reactions, View all Careers. sharing sensitive information, make sure youre on a federal Pityriasis Rosea. Bethesda, MD 20894, Web Policies Pityriasis rosea (PR)-like eruption is a cutaneous complication associated with several medications and vaccinations. (2020) 33:e13878. World J Clin Cases. (2021) 35:e5468. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Published by Wolters Kluwer Health, Inc. Refined carbohydrates, such as sugar, pastries and white bread. Allergy Asthma Proc. Drago F, Ciccarese G, Javor S, et al. PMC J Med Virol. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753512/), Visitation, mask requirements and COVID-19 information, sexually transmitted disease or infection. Cutaneous Eruptions in the Course of COVID-19 Among Geriatric Patients in a Nursing Home in Poland. J Eur Acad Dermatol Venereol. eCollection 2022. Lessons: As vaccine reactogenicity reports continue to surface, dermatologists and other health care providers should understand the landscape of the latest cutaneous reactions to guide and address patients' concerns. J Eur Acad Dermatol Venereol 2016; 30: 544-545. Patient concerns: Here, we described a case of PR-like eruption that developed 14 days after Oxford/AstraZeneca vaccination in a 52-year-old Thai woman with glioblastoma. Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same . Some treatments can alleviate related symptoms, including itching. Many Americans become infected with them at an early age. Table 1. Conflicts of Interests: The authors declare there are no competing interests. PS conceptualized the case report and revised the manuscript. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. However, there isnt enough research to determine that stress may cause pityriasis rosea. Herald patch in the right hypochondrium followed by typical oval-shaped secondary plaques, Pityriasis rosea lesions on the upper extremities, MeSH Adverse cutaneous reactions following COVID-19 vaccines have increased, highlighting not only how SARS-CoV-2 infection but also COVID-19 vaccines may induce adverse cutaneous manifestations. Careers. and transmitted securely. Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review. While home remedies are safe for most people, its a good idea to check with your healthcare provider before trying some of the following options. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature JAAD Int. They develop in a pattern that resembles sagging Christmas tree branches. Dermatol Ther. "In studies, between 2 and 3 percent of people develop the disease again. Unable to load your collection due to an error, Unable to load your delegates due to an error. These findings were consistent with a diagnosis of PR-like eruption. Epub 2022 Jan 31. Polack FP, Thomas SJ, Kitchin N, et al. Women and young people are most likely to have these reactions. J Eur Acad Dermatol Venereol. Bookshelf 2022 Nov 1;43(6):555-558. doi: 10.2500/aap.2022.43.220058. However, if you experience any symptoms, therapy can provide relief. doi: 10.1111/jdv.12942, 13. In: Knoop KJ, Stack LB, Storrow AB, et al., eds. The Covid Symptom Study. In: Jameson J, Fauci AS, Kasper DL, et al., eds. Adya KA, Inamadar AC, Albadri W. Post Covid-19 vaccination papulovesicular pityriasis rosea-like eruption in a young male. The site is secure. A more recent letter in the International Journal of Dermatology reported a "unique case of pityriasis rosea following administration of mRNA COVID-19 vaccine." 2022 Dec;9:127. doi: 10.1016/j.jdin.2022.03.018. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. However, after 14 days, she developed multiple discrete blanching erythematous oval patches and plaques on the lower abdomen, back, and bilateral upper thighs (Figures 1A,B). Disclaimer. 2021 Aug;185(2):e34. Moreover, while dermoscopy may facilitate the diagnosis of PR, its utility for atypical PR or PR-like lesions is still limited. Int J Infect Dis. Marcantonio-Santa Cruz OY, Vidal-Navarro A, Pesqu D, Gimnez-Arnau AM, Pujol RM, Martin-Ezquerra G. J Eur Acad Dermatol Venereol. Would you like email updates of new search results? 2021;185(2):e34. Abdullah L, Hasbani D, Kurban M, Abbas O. Pityriasis rosea after mRNA COVID-19 vaccination. Clipboard, Search History, and several other advanced features are temporarily unavailable. 2023 Cond Nast. Numerous scattered erythematous, Pityriasis rosea. A spectrum of cutaneous reactions to SARs-CoV-2 (COVID-19) vaccines have been reported in the literature. -, Busto-Leis J.M., Servera-Negre G., Mayor-Ibarguren A., et al. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. Federal government websites often end in .gov or .mil. McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, et al. A virus may cause pityriasis rosea, but experts arent sure. 2021 Nov;35(11):e721-e722. Em Rata Just Debuted a Chic Italian Bob With Baby Bangs. COVID-19 vaccines reactions, type I hypersensitivity reactions (such as urticaria, angioedema, and anaphylaxis), . Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Int J Dermatol. Unauthorized use of these marks is strictly prohibited. Bathe or shower in lukewarm water. Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of COVID19. official website and that any information you provide is encrypted and transmitted securely. doi: 10.1097/MD.0000000000029823. See this image and copyright information in PMC. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Foods that have anti-inflammatory properties include: Foods that may increase inflammation include: There isnt any way to prevent pityriasis rosea. For instance, the rash sometimes appears only under the arms or on the flanks. Cleveland Clinic is a non-profit academic medical center. Rashes should be considered a "key diagnostic sign" of Covid-19, according to a study, which found 8% of people who test positive for the virus have some form of rash. 2022 Mar 15;10(3):624. doi: 10.3390/microorganisms10030624. Use of this site constitutes acceptance of our If you develop symptoms of pityriasis rosea while pregnant, contact your healthcare provider right away. 8 In some cases, antibodies against HHV6/7 as well as viral DNA in plasma and PBMCs were detected. Pityriasis rosea often occurs this way, but not always. (2006) 12:1. doi: 10.5070/D380D8301D, 11. and transmitted securely. It was found on younger COVID-19 patients suffering milder forms of the virus. eCollection 2022. doi: 10.1111/ajd.13504. FOIA A variant called inverse pityriasis rosea can affect the skin on your neck, face, armpits (axillae) and groin, though it isnt common. Treatment with topical 0.1% triamcinolone acetonide twice daily showed partial response after seven days. Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders. It said blood spots under the skin might also be present, either as spots or dots or on larger areas. Pityriasis Rosea as a Possible Complication of Vaccination Against COVID-19. Of the reported cases, 96.7% were secondary to the Pfizer vaccine, with only 1 reported . Atypical pityriasis rosea associated with mRNA COVID19 vaccine E. Bostan, Adam Jarbou Published 29 September 2021 Medicine Journal of Medical Virology Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of Covid-19. 2022 Feb 3;9 (2):003164. doi: 10.12890/2022_003164. Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. Among patients who received inactivated vaccines, another case of PR-like eruption was reported four days after the first dose of CoronaVac (SinoVac) (1). doi: 10.1111/j.0022-202X.2005.23719.x. Following the national COVID-19 vaccination guidelines, she received a shot of ChAdOx1 nCoV-19 (AZD1222) vaccine before the therapy. Disclaimer. 8 PDF Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases D. McMahon, E. Amerson, +11 authors E. Freeman Medicine -, Carballido Vzquez A.M., Morgado B. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. You may initially develop a fever, headache or upper respiratory infection. PMC We evaluated the clinical and pathologic spectrum of mucocutaneous reactions following COVID-19 vaccines, observed consecutively within three large tertiary Centers of the Metropolitan City of Milan . Moreover, COVID-19 may solely induce human herpesvirus reactivation through the immunomodulatory ability of SARS-CoV-2 to reactivate latent viruses (8, 9). 2022 Jul 8;101(27):e29823. Epub 2022 Jun 19. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. J Formos Med Assoc. Get more info about other skin conditions: The Ultimate Guide to Skin Conditions for Black & Brown Folks, I Thought I Just Had Dry Skin, But It Was Actually Perioral Dermatitis, Everything You Should Know About Hidradenitis Suppurativa. Epub 2021 May 29. Pityriasis rosea is a rash that usually appears on the torso, upper arms, thighs or neck. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases. It should clear your body in six to eight weeks. Human herpesvirus-6, -7, and Epstein-Barr virus reactivation in pityriasis rosea during COVID-19. Oily fish, such as mackerel, salmon or sardines. 2021 Sep 7;8:752443. doi: 10.3389/fmed.2021.752443. Figure 3. Got an extremely itchy rash that came seemingly out of nowhere? Epub 2022 Jan 5. These types cannot cause cold sores or genital herpes. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance. F. Drago, G. Ciccarese, A. Parodi government site. While annoyingly itchy, the rash does not cause any serious long-term side effects and is not contagious, unlike the diseases these vaccines protect against. J Eur Acad Dermatol Venereol. A few days later, the cluster came: Ten little dots arranged themselves in a perfect alien-like crop circle on my upper back, and they itched so much that I scratched them raw. "Sometimes it can spread to what we called the proximal extremities, meaning the parts that are closer to the trunk, so the shoulders, upper arms, [and] the thighs," she says. The authors of one 2014 case report of a 71-year-old man who suffered from pityriasis rosea one month after receiving an influenza vaccine concluded that "altered immunity" could result in reactivation of HHV-6 and/or HHV-7 which may have triggered an atypical presentation of PR. Please enable it to take advantage of the complete set of features! "Other treatments including phototherapy or oral medications can be considered for extensive or persistent cases, [and] some small case studies support the use of oral antivirals like acyclovir or oral anti-inflammatory antibiotics erythromycin," King explains. Pityriasis rosea is a common condition that causes discolored patches on your skin. -, Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. JAAD Case Rep. 2021;7:9394. Would you like email updates of new search results? Federal government websites often end in .gov or .mil. Dermoscopy showed dotted and linear vessels forming a network on a yellowish background, with some whitish peripheral scales (Figure 3A). The condition is more prevalent in spring and fall. 8:752443. doi: 10.3389/fmed.2021.752443. Medicine (Baltimore). Epub 2022 May 31. 2021 Jun 25;118(25):431. doi: 10.3238/arztebl.m2021.0257. See this image and copyright information in PMC. Physicians should be aware that pityriasis rosea is a rare side-effect of COVID-19 vaccination.Pityriasis rosea is self-limiting and no medical treatment is usually required. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. However, adverse effects to COVID-19 vaccines, particularly cutaneous reactions, have been reported. In conclusion, we have described the first case of PR-like eruption following ChAdOx1 nCoV-19 (Oxford/AstraZeneca) vaccination. This tiny glimpse of her natural texture is thrilling. However, some people believe that eating an anti-inflammatory diet may relieve itching. Outcome: Int J Dermatol. Med Clin (Barc). The study said the appearance was similar to pityriasis rosea, a common skin condition. -, Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, Franco-Marquez R, Arvizu-Rivera RI. -. 8600 Rockville Pike I put on some hydrocortisone and went to sleep, then woke up with another mark on my side, a couple inches below my armpit. Disclaimer. Epub 2021 Aug 26. Dermatol Ther. sharing sensitive information, make sure youre on a federal 2020 Sep 25;155(6):273. doi: 10.1016/j.medcli.2020.05.024. New York City-based dermatologist Macrene Alexiades. Drago F, Ciccarese G, Javor S, Parodi A. Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. 2022 Jan;114:88-89. doi: 10.1016/j.ijid.2021.10.055. "It looks very different.". Shabazz DR. Pityriasis Rosea. While you don't need to treat the rash, some patients ask for treatment to take care of the following. Anyone can get pityriasis rosea. See this image and copyright information in PMC. . 2022 Jul 21;14(7):e27108. However, if it does, the symptoms may last for a longer period. FOIA Received: 03 August 2021; Accepted: 17 August 2021; Published: 07 September 2021. Accessibility National Library of Medicine Moreover, central dusky-red erythematous was observed on some plaques (Figure 2A). (2021). The https:// ensures that you are connecting to the Ciccarese G, Parodi A, Drago F. SARS-CoV-2 as possible inducer of viral reactivations. 2022 Mar 15;10(3):624. doi: 10.3390/microorganisms10030624. The https:// ensures that you are connecting to the Birlutiu V, Dobritoiu ES, Lupu CD, Herteliu C, Birlutiu RM, Dragomirescu D, Vorovenci A. This site needs JavaScript to work properly. Herzum A, Trave I, D'Agostino F, Burlando M, Cozzani E, Parodi A. Clin Exp Vaccine Res. Martn Enguix D, Salazar Nievas MDC, Martn Romero DT. Copyright 2021 the Author(s). Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. A 3-cm oval plaque with peripheral scale, larger, MeSH eCollection 2022. Copyright 2021 Leerunyakul, Pakornphadungsit and Suchonwanit. Though there's no single-known cause, it may be brought on by a drug interaction, or the reactivation of herpes simplex virus 6 or 7. Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. PMC These skin conditions can include, among other things, hives, measles-like rashes and a full body rash similar to pityriasis rosea. doi: 10.1016/j.jaad.20.2103.092. Histopathological findings of pityriasis rosealike eruption in patient 1. Pityriasis rosea-like eruption presenting as multiple discrete erythematous oval patches and plaques on the back (A) lower abdomen, and bilateral upper thighs (B); lesions distributed along cleavage lines without prominent scales (C). -. Flares of other types of skin conditions [like psoriasis] sometimes have been described as well," says Lam. Although histopathologic characteristics of PR are also observed in PR-like lesions, the presence of dyskeratotic keratinocytes, interface dermatitis, and eosinophilic infiltration in the dermis may be more prominent in PR-like eruptions (11). Drago F, Ciccarese G, Rebora A, Parodi A. A 52-year-old Thai woman with a one-year history of recurrent glioblastoma was admitted to our hospital for a planned targeted therapy. No one knows what causes pityriasis rosea, though healthcare experts think a virus might be responsible. (Unfortunately, I scratched my rash until it bled, so my hyperpigmentation may linger.). . Epub 2021 Apr 26. Oueijan RI, Hill OR, Ahiawodzi PD, Fasinu PS, Thompson DK. HHS Vulnerability Disclosure, Help (No.) 2021;35(8):e489e491. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). COVID-19 has been reported as one such viral trigger for PR. Diagnoses: Epub 2021 Aug 7. Pityriasis is linked mainly with herpesviruses 6 and 7; only a . An official website of the United States government. To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. Hum Vaccin Immunother. National Library of Medicine eCollection 2022. In approximately 50% of people with pityriasis rosea, the patches itch. Cureus. (2020) 83:e5760. Before Human herpesvirus-6,7, and Epstein-Barr virus reactivation in pityriasis rosea during COVID-19. HHS Vulnerability Disclosure, Help An official website of the United States government. Clinical findings of pityriasis rosealike eruption in the patients. If you have pityriasis rosea, it can generally be well-managed without any treatment. Among patients who received COVID-19 vaccines, PR-like eruptions have been reported following the first (n = 1) or second dose (n = 2) of BNT162b2 mRNA-based vaccines (3, 4). Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, et al. PMC It often presents with diffuse and confluent severely pruritic dusky-red erythematous lesions in the absence of herald patch (11). (2015) 2015:253154. doi: 10.1155/2015/253154, 14. The .gov means its official. However, pityriasis rosea can look similar to other skin conditions, including: If theres any doubt, your healthcare provider may perform the following tests: In most cases, pityriasis rosea goes away without any treatment in six to eight weeks. Pityriasis rosea (pih-tuh-RY-uh-sis ROH-zee-uh) is a common skin condition that causes patches of your skin to develop raised, scaly rashes. J Eur Acad Dermatol Venereol 2020;34:e2123. Clipboard, Search History, and several other advanced features are temporarily unavailable. It was described as "clinically reminiscent" of pityriasis rosea by the authors, from the divisions of dermatology and venereology, pathology, intensive care, and the virology laboratory, of the Hpital Cochin, Paris. Herein, we are reporting a unique. -, Polack FP, Thomas SJ, Kitchin N et al. The ones found in people with pityriasis rosea are human herpesviruses 6 and 7. Med. Careers. JAAD Int. Bethesda, MD 20894, Web Policies MeSH Six cases of pityriasis rosea following SARS-CoV-2 vaccination with BNT162b2. 2022 Oct;123:58-69. doi: 10.1016/j.ijid.2022.06.037. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature. Common causes of drug-induced PR-like eruptions include angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, and gold. In addition to COVID-19 vaccination, she was currently taking medications (i.e., levetiracetam and thyroxin) for glioblastoma, and the two drugs had been prescribed for approximately nine months. J Eur Acad Dermatol Venereol. Br J Dermatol 2020; 183: 431442. Your rash looks infected (red, purple, gray or white skin; irritation and swelling). Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. Coronavirus disease 2019 and pityriasis rosea: A review of the immunological connection. Epub 2021 Jun 10. Would you like email updates of new search results? -. Pityriasis rosea and pityriasis rosea-like eruptions after COVID-19 vaccines. Dermatologic side effects of COVID-19 vaccines range from morbilliform rash and pernio to pityriasis rosea and erythema multiforme. Epub 2021 Aug 7. doi: 10.1016/j.jaad.2020.04.094, 8. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection J Eur Acad Dermatol Venereol. See this image and copyright information in PMC. 2021 Nov 2;17(11):4097-4098. doi: 10.1080/21645515.2021.1963173. Keywords: Epstein-Barr virus reactivation after COVID-19 vaccination in a young immunocompetent man: a case report. Epub 2022 Feb 9. Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same vaccine. 7 Articles, This article is part of the Research Topic, Creative Commons Attribution License (CC BY), Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Studies show that the development of pityriasis rosea during pregnancy may cause birth complications, including miscarriage and poor muscle tone and development once the baby is born (neonatal hypotonia). 2022 Aug;87(2):295. doi: 10.1016/j.jaad.2022.06.036. -, Broccolo F, Drago F, Careddu AM, et al. Federal government websites often end in .gov or .mil. Once its gone, you likely wont develop it again. The evolution was unfavorable, with the spread of the lesions and the accentuation of the pruritus. HHS Vulnerability Disclosure, Help From grooming sets to self-care gadgets, we've got them covered. An official website of the United States government. In a registry-based study, PR-like eruption was observed in only 12% of patients (14). eCollection 2022. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 Vaccine. Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Microorganisms. Figure 1. Safety and efficacy of the BNT162b2 mRNA Covid19 vaccine. Dermatol Ther. One case of pityriasis rosea is reported in a patient infected with COVID19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. It is increasingly recognized that SARS-CoV-2 infection and COVID-19 vaccines have been associated with skin disorders, including pityriasis rosea. Pityriasis means scaly, and rosea means pink, but the rashes may look red, gray, brown or purple. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. FOIA NCI CPTC Antibody Characterization Program, Ehsani AH, Nasimi M, Bigdelo Z. Pytiriasis rosea as a cutaneous manifestation of COVID-19 infection. 2021 Oct;20(10):3080-3084. doi: 10.1111/jocd.14372. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. Like previously reported cutaneous eruptions associated with COVID-19 infection, these cases "raise more questions than . 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Epub 2021 Jul 21. Few brownish patches also appeared, suggestive of post-inflammatory hyperpigmentation. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine. Here, we describe a case of PR-like eruption following ChAdOx1 nCoV-19 (AZD1222) vaccination in a Thai patient with glioblastoma. Pityriasis lichenoides is a clonal T-cell disorder that may develop in response to foreign antigens (eg, infections or drugs) and may be associated with cutaneous T-cell lymphoma. Among the common cutaneous manifestations of COVID-19 (e.g., morbilliform eruptions, chilblains, and varicella-like vesicles), PR and PR-like eruptions have rarely been described (6, 7). COVID-19-associated pityriasis rosea in children: Case report and literature review. Epub 2022 Feb 9. Clipboard, Search History, and several other advanced features are temporarily unavailable. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. (a) Patient 1: Thin, Histopathological findings of pityriasis rosealike, Histopathological findings of pityriasis rosealike eruption in patient 1. Temiz SA, Abdelmaksoud A, Dursun R, Durmaz K, Sadoughifar R, Hasan A. J Cosmet Dermatol. The significance of investigating clinical, histopathologic and virological features in pityriasis rosea and pityriasis rosea-like eruptions following COVID-19 vaccinations. Accessibility Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. Bookshelf Department of Dermatology, Graduate School of Medicine, Kyusyu University, Japan. The rash itself usually doesnt blister or bleed, but in many cases, the skin may peel. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Blumenthal KG, Fox LP, Freeman EE.