Accessibility Talking with a counselor might help. The supplement is making real changes in my body and mind, and it feels incredible. This is a condition characterized by an enlarged prostate. When you are on TRT, your DHT levels tend to go out of the normal range and finasteride is a mechanism for bringing it back into range. Better to learn the cause of PFS and create a cure based on that. Adverse side effects of 5-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients. Drugs generally won't help if retrograde ejaculation is due to surgery that causes permanent physical changes of your anatomy. doi: 10.1210/jc.2016-2726. WebHow to Correct Post Finasteride Syndrome Minimize Stressors. Advertising revenue supports our not-for-profit mission. PMC WebPost finasteride syndrome is real. I dunno, I dont get it. If your doctor thinks drugs you are taking might be affecting your ability to ejaculate normally, he or she might have you stop taking them for a period of time. I has numbness also. Taking a vitamin D supplement or getting moderate sun exposure on a daily basis could be helpful in restoring your bodys vitamin D levels. People with post finasteride syndrome can have increased food sensitivities, extreme mood swings, and low energy levels. Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients. Yeah, yeah. This is not proof that finasteride is to blame, since a variety of medical conditions and other prescription drugs could explain the sexual symptoms. Your doctor might ask: Mayo Clinic does not endorse companies or products. Last time I was on there they had started discussing some relationships between HCG and Thyroid? Disorders of male orgasm and ejaculation. I suggest you see an expert for internal workup, we do this frequently in our practice. Adverse effects of common medications on male fertility. This area was the most recovery and reversal of symptoms. Disclaimer. 2018;120:143149. The number of men sharing their experience of Post-Finasteride Syndrome is steadily rising, painting a bleak picture of the life-shattering effects the drug can have. A mod answered and I answered the guy in a normal way, but they deleted my reply and blocked my account. Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. Melcangi RC, Caruso D, Abbiati F, Giatti S, Calabrese D, Piazza F, Cavaletti G. J Sex Med. Contemporary management of disorders of male orgasm and ejaculation. What's the best treatment to use to try to get my partner pregnant? For details, see text., Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, andmore. I suspect its because my E2 was so low already and that made it feel even lower (single digits if I recall correctly). I tried just about everything over 11 years. I dont really understand why theyre like that. In: Ferri's Clinical Advisor 2022. To be honest, I think for the most part these recoveries werent PFS but rather hormonal imbalances. .FIYolDqalszTnjjNfThfT{max-width:256px;white-space:normal;text-align:center} 2019;16 doi: 10.3390/ijerph16101726. Accessed Sept. 15, 2016. I recovered and I hope all of you suffering from PFS recover too. After a few days I starting liking women again and became sexually from frustrated. The .gov means its official. Mods are always talking about the survey too, I said a survey wont cure us and we could be be waiting for 10 years if we dont do anything. I have the desire for sex and intimacy but my brain simply wont communicate with my penis when its time for intercourse. Samplaski MK, et al. You can't get worse than living with no dick dude. Archivio Istituzionale della Ricerca Unimi, NCI CPTC Antibody Characterization Program, Agis-Balboa R.C., Guidotti A., Pinna G. 5alpha-reductase type I expression is downregulated in the prefrontal cortex/Brodmann's area 9 (BA9) of depressed patients. An official website of the United States government. (photo). sharing sensitive information, make sure youre on a federal I took a step back and said forget about PFS with these blood tests and these symptoms, whats the normal course of action? This type of damage can be caused by diabetes, multiple sclerosis, certain surgeries, and other conditions and treatments. Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight lossfrom exercises to build a stronger core to advice on treating cataracts. When dosed properly, it can bring DHT within normal ranges very effectively. Day 1 I felt no difference. http://www.resolve.org/about-infertility/what-is-infertility/frequently-asked-questions-about-infertility.html. 2013 Oct;10(10):2598-603. doi: 10.1111/jsm.12269. What is infertility? And posted the article and some cliffs about his solution. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Book: Mayo Clinic Guide to Fertility and Conception. Yeah the joe_kool guy or whatever his name is had really good luck with TRT, he is honestly the reason I went down this road. 5alpha-reductase; Androgenetic alopecia; Depression; Finasteride; Neuroactive steroids; Sexual dysfunction. Nature Reviews Urology. Clinical features reported in patients affected by post-finasteride syndrome. Finasteride causes cognitive & sexual decline. Note that prior to this protocol I tried injectable Test enanthate, Masteron, proviron and hcg which made my condition even worse. I could be wrong but none of them seem to have anhedonia or genital numbness or fatigue or insomnia or anything, just libido and ED issues. Examples include bladder neck surgery and transurethral resection of the prostate. Retrograde ejaculation can be especially challenging if you and your partner want to conceive a child. breast enlargement. Merck developed finasteride in the 1980s. Stop watching porn, stop masturbating, forget about sex, meditate, take cold showers, try breathing exercises, try extended water fasting. ._1EPynDYoibfs7nDggdH7Gq{margin-bottom:8px;position:relative}._1EPynDYoibfs7nDggdH7Gq._3-0c12FCnHoLz34dQVveax{max-height:63px;overflow:hidden}._1zPvgKHteTOub9dKkvrOl4{font-family:Noto Sans,Arial,sans-serif;font-size:14px;line-height:21px;font-weight:400;word-wrap:break-word}._1dp4_svQVkkuV143AIEKsf{-ms-flex-align:baseline;align-items:baseline;background-color:var(--newCommunityTheme-body);bottom:-2px;display:-ms-flexbox;display:flex;-ms-flex-flow:row nowrap;flex-flow:row nowrap;padding-left:2px;position:absolute;right:-8px}._5VBcBVybCfosCzMJlXzC3{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:21px;color:var(--newCommunityTheme-bodyText)}._3YNtuKT-Is6XUBvdluRTyI{position:relative;background-color:0;color:var(--newCommunityTheme-metaText);fill:var(--newCommunityTheme-metaText);border:0;padding:0 8px}._3YNtuKT-Is6XUBvdluRTyI:before{content:"";position:absolute;top:0;left:0;width:100%;height:100%;border-radius:9999px;background:var(--newCommunityTheme-metaText);opacity:0}._3YNtuKT-Is6XUBvdluRTyI:hover:before{opacity:.08}._3YNtuKT-Is6XUBvdluRTyI:focus{outline:none}._3YNtuKT-Is6XUBvdluRTyI:focus:before{opacity:.16}._3YNtuKT-Is6XUBvdluRTyI._2Z_0gYdq8Wr3FulRLZXC3e:before,._3YNtuKT-Is6XUBvdluRTyI:active:before{opacity:.24}._3YNtuKT-Is6XUBvdluRTyI:disabled,._3YNtuKT-Is6XUBvdluRTyI[data-disabled],._3YNtuKT-Is6XUBvdluRTyI[disabled]{cursor:not-allowed;filter:grayscale(1);background:none;color:var(--newCommunityTheme-metaTextAlpha50);fill:var(--newCommunityTheme-metaTextAlpha50)}._2ZTVnRPqdyKo1dA7Q7i4EL{transition:all .1s linear 0s}.k51Bu_pyEfHQF6AAhaKfS{transition:none}._2qi_L6gKnhyJ0ZxPmwbDFK{transition:all .1s linear 0s;display:block;background-color:var(--newCommunityTheme-field);border-radius:4px;padding:8px;margin-bottom:12px;margin-top:8px;border:1px solid var(--newCommunityTheme-canvas);cursor:pointer}._2qi_L6gKnhyJ0ZxPmwbDFK:focus{outline:none}._2qi_L6gKnhyJ0ZxPmwbDFK:hover{border:1px solid var(--newCommunityTheme-button)}._2qi_L6gKnhyJ0ZxPmwbDFK._3GG6tRGPPJiejLqt2AZfh4{transition:none;border:1px solid var(--newCommunityTheme-button)}.IzSmZckfdQu5YP9qCsdWO{cursor:pointer;transition:all .1s linear 0s}.IzSmZckfdQu5YP9qCsdWO ._1EPynDYoibfs7nDggdH7Gq{border:1px solid transparent;border-radius:4px;transition:all .1s linear 0s}.IzSmZckfdQu5YP9qCsdWO:hover ._1EPynDYoibfs7nDggdH7Gq{border:1px solid var(--newCommunityTheme-button);padding:4px}._1YvJWALkJ8iKZxUU53TeNO{font-size:12px;font-weight:700;line-height:16px;color:var(--newCommunityTheme-button)}._3adDzm8E3q64yWtEcs5XU7{display:-ms-flexbox;display:flex}._3adDzm8E3q64yWtEcs5XU7 ._3jyKpErOrdUDMh0RFq5V6f{-ms-flex:100%;flex:100%}._3adDzm8E3q64yWtEcs5XU7 .dqhlvajEe-qyxij0jNsi0{color:var(--newCommunityTheme-button)}._3adDzm8E3q64yWtEcs5XU7 ._12nHw-MGuz_r1dQx5YPM2v,._3adDzm8E3q64yWtEcs5XU7 .dqhlvajEe-qyxij0jNsi0{font-size:12px;font-weight:700;line-height:16px;cursor:pointer;-ms-flex-item-align:end;align-self:flex-end;-webkit-user-select:none;-ms-user-select:none;user-select:none}._3adDzm8E3q64yWtEcs5XU7 ._12nHw-MGuz_r1dQx5YPM2v{color:var(--newCommunityTheme-button);margin-right:8px;color:var(--newCommunityTheme-errorText)}._3zTJ9t4vNwm1NrIaZ35NS6{font-family:Noto Sans,Arial,sans-serif;font-size:14px;line-height:21px;font-weight:400;word-wrap:break-word;width:100%;padding:0;border:none;background-color:transparent;resize:none;outline:none;cursor:pointer;color:var(--newRedditTheme-bodyText)}._2JIiUcAdp9rIhjEbIjcuQ-{resize:none;cursor:auto}._2I2LpaEhGCzQ9inJMwliNO,._42Nh7O6pFcqnA6OZd3bOK{display:inline-block;margin-left:4px;vertical-align:middle}._42Nh7O6pFcqnA6OZd3bOK{fill:var(--newCommunityTheme-button);color:var(--newCommunityTheme-button);height:16px;width:16px;margin-bottom:2px} Almost starting to think like a conspiracy theorist. This is a summary of the protocol which I followed for 6 months which eventually cured me. Elsevier; 2022. https://www.clinicalkey.com. -, Alkahtane A.A., Albasher G., Al-Sultan N.K., Alqahtani W.S., Alarifi S., Almeer R.S., Alghamdi J., Ali D., Alahmari A., Alkahtani S. Long-term treatment with finasteride induces apoptosis and pathological changes in female mice. Andracim Gel (small 2 eminem size, 1 on each size of rib cage, less is more with this stuff). Please enable it to take advantage of the complete set of features! Plentiful in opinions, short on facts. AR: androgen receptor; DHP: dihydroprogesterone; DHT: dihydrotestosterone; ER: estrogen receptor beta; PR: progesterone receptor; PROG: progesterone; T: testosterone; THP: tetrahydroprogesterone. The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School. Around 8 months and i was pretty much recovered. Just bombarding their bodies with strong androgens. @keyframes _1tIZttmhLdrIGrB-6VvZcT{0%{opacity:0}to{opacity:1}}._3uK2I0hi3JFTKnMUFHD2Pd,.HQ2VJViRjokXpRbJzPvvc{--infoTextTooltip-overflow-left:0px;font-size:12px;font-weight:500;line-height:16px;padding:3px 9px;position:absolute;border-radius:4px;margin-top:-6px;background:#000;color:#fff;animation:_1tIZttmhLdrIGrB-6VvZcT .5s step-end;z-index:100;white-space:pre-wrap}._3uK2I0hi3JFTKnMUFHD2Pd:after,.HQ2VJViRjokXpRbJzPvvc:after{content:"";position:absolute;top:100%;left:calc(50% - 4px - var(--infoTextTooltip-overflow-left));width:0;height:0;border-top:3px solid #000;border-left:4px solid transparent;border-right:4px solid transparent}._3uK2I0hi3JFTKnMUFHD2Pd{margin-top:6px}._3uK2I0hi3JFTKnMUFHD2Pd:after{border-bottom:3px solid #000;border-top:none;bottom:100%;top:auto} Ive seen this several times over there. Jefferys A, et al. Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron. Your doctor will ask you questions about your health and symptoms. https://forum.propeciahelp.com/t/i-think-im-healed-after-six-year-nightmare/35477. The symptoms of PFS start to subside within four to eight months after discontinuing the medicine. These include: Prostate pain Persistent fatigue, exhaustion Stomach pains and digestive problems Constipation Blurry vision Propecia is the Biggest Regret of my Life Taking Propecia is the biggest regret of my life, PK said. Now I can happily say that I no longer have any problem, strong erection all day and all night. Before ._1sDtEhccxFpHDn2RUhxmSq{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;display:-ms-flexbox;display:flex;-ms-flex-flow:row nowrap;flex-flow:row nowrap}._1d4NeAxWOiy0JPz7aXRI64{color:var(--newCommunityTheme-metaText)}.icon._3tMM22A0evCEmrIk-8z4zO{margin:-2px 8px 0 0} 2011 Mar;8(3):872-84. doi: 10.1111/j.1743-6109.2010.02157.x. Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: Imipramine, an antidepressant. Feeling dissociated and never present. The problem is that most docs prescribe it at excessively high levels (5 mg/day). 2022 Apr;181:157-166. doi: 10.1016/j.brainresbull.2022.01.020. Unauthorized use of these marks is strictly prohibited. https://forum.propeciahelp.com/t/my-story-yes-it-was-messy-and-yes-i-am-fine-now/5456. Resolve: The National Infertility Association. I took a large amount of DHT (proviron) for 7 weeks at 200 mg per day to reduce receptor sensitivity to DHT. Endocrinol. They claim its more to cover their ass because they dont want people trying whatever unproven solution and get worse and commit suicide or something. Will medications help me ejaculate normally? doi: 10.1007/s00213-014-3567-5. Its H.C.G (HCG) dosed at 250IU Monday, Wednesday and Friday only. To diagnose retrograde ejaculation, your doctor may: If you have dry orgasms, but your doctor doesn't find semen in your bladder, you might have a problem with semen production. WebI cannot say enough about this. After a bit over a week I decreased the dose to 10mg before bedtime and none in the afternoon. Since it only comes in 5 and 1 mg pills, there isnt much of a choice. The only thing that makes sense is to push your androgen receptors and epigenetics the opposite way fin did. I did three months on testosterone injections and muscle building. This stuff WORKS. Traish AM, Melcangi RC, Bortolato M, Garcia-Segura LM, Zitzmann M. Rev Endocr Metab Disord. I just decided to get back on gear after a year off + dutasteride during that time. Long term HCG treatment at high dosages can cause issues. -, Baas W.R., Butcher M.J., Lwin A., Holland B., Herberts M., Clemons J., Delfino K., Althof S., Kohler T.S., McVary K.T. Res. Minoxidil is FDA approved for genetic hair loss - it does not help other conditions quite so much. Minoxidil takes 4-6 months before an individual should assess whether or not it helps. You're right. For what it's worth, here's a couple similar success stories involving numbness, but from PSSD instead of PFS: Testosterone along with initial estrogen management , completely cured my pssd, everything from numbness, to hard on quality , no morning wood, to actually having sexual desires again. What was the article? Metab. https://old.reddit.com/r/steroids/comments/m5m7o9/help_steroids_for_pssd/gr0uhqj/. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. A community dedicated to people suffering long term effects after taking 5-ar inhibitors such as Propecia/Finasteride, or for people who wish to know more about the constellation of symptoms commonly known as Post Finasteride Syndrome. HHS Vulnerability Disclosure, Help Authors received funding from the Post-Finasteride Foundation in order to study PFS symptomatology of patients and in experimental models. A. Finasteride (sold as Proscar and generic brands) is prescribed for symptoms of an enlarged prostate; it's also used at a lower strength (under the name Propecia) for male pattern baldness. And youre competely right, they make it sound like youre doomed and you shouldnt try anything but wait for the Baylor study and fill out the surveyDo they really expect some magical cure to come out when Baylor releases or their survey has enough participants? ._3Z6MIaeww5ZxzFqWHAEUxa{margin-top:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._3EpRuHW1VpLFcj-lugsvP_{color:inherit}._3Z6MIaeww5ZxzFqWHAEUxa svg._31U86fGhtxsxdGmOUf3KOM{color:inherit;fill:inherit;padding-right:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._2mk9m3mkUAeEGtGQLNCVsJ{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;color:inherit} Indian J Plast Surg. What is likely causing my symptoms or condition? My personal experience is that finasteride is an important medication for older guys on TRT that are experiencing BPH. https://old.reddit.com/r/PostFinSyndrome/comments/ogcsjc/i_recovered_from_pfs_it_is_possible/. Next to no sensitivity in my genitals. Other: Issues retaining and producing muscle, rectal muscle pain, spike in lower-abdomen fat, also has anyone noticed a rapid increase in earwax production? Energy-boosting coffee alternatives: What to know. Therefore, results here discussed indicate that PFS is an emerging clinical problem that needs to be further elucidated. Finasteride (Propecia) is a medication that can help treat MPB by lowering levels of DHT. As here reported, these observations are mainly based on self-reporting of the symptomatology by the patients and few clinical studies have been performed so far. Incredible! This content does not have an Arabic version. -, Basaria S., Jasuja R., Huang G., Wharton W., Pan H., Pencina K., Li Z., Travison T.G., Bhawan J., Gonthier R., Labrie F., Dury A.Y., Serra C., Papazian A., O'Leary M., Amr S., Storer T.W., Stern E., Bhasin S. Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. I did a cycle of hcg 250ui m/w/f for 6 months + a week and a half of clomid 25 everyday + DHEA (I know I'm a idiot) More or less cured me from no low libido and all that great stuff for over a year now and I'm off everything. Ask questions about your symptoms and how long you've had them. Took finasteride for 5 months. Mehta A, et al. However, the side effects of a medication usually go away when you stop taking it. Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron, of course he doesnt have any affliate links to those products. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. 2015;12:401. Or at the very least allow people to post ideas. Many men with retrograde ejaculation are able to get their partners pregnant once they seek treatment. 2022 Jul 27;15(8):930. doi: 10.3390/ph15080930. ._2Gt13AX94UlLxkluAMsZqP{background-position:50%;background-repeat:no-repeat;background-size:contain;position:relative;display:inline-block} I know how I feel and I know it's working. ._12xlue8dQ1odPw1J81FIGQ{display:inline-block;vertical-align:middle} The site is secure. Are there other possible causes for my symptoms or condition? Preparing a list of questions before your appointment can help you make the most of your time together. Should I be concerned? Essentially I took testosterone exogenously And I took hcg afterwards, https://old.reddit.com/r/PSSD/comments/7lfc1e/how_i_fixed_my_pssd/. This site complies with the HONcode standard for trustworthy health information: verify here. You are spreading nonsense, people have been trying that crap for years to no effect. https://www.hairlosstalk.com/interact/threads/how-i-cured-my-problem-with-post-finasteride-syndrome.125634/. Respectfully, I don't care what the article says. Tamoxifen I did 20mg during the four weeks every day. Yeah, that guy's comment history is really puzzling: When i dared visit PFS forums, the most miserable users there were still in a better state than me. I understand theyre trying to cover their ass but its the users responsibility if he wants to try it or not so the forum is not liable at all. Diagnosing and Reversing It", Is Post Finasteride Syndrome Real? Toxicol. So yes, it is not Dermatologic Surgeon, Board Certified in Dermatology, How Long Does Minoxidil 5 Take to Work? @keyframes ibDwUVR1CAykturOgqOS5{0%{transform:rotate(0deg)}to{transform:rotate(1turn)}}._3LwT7hgGcSjmJ7ng7drAuq{--sizePx:0;font-size:4px;position:relative;text-indent:-9999em;border-radius:50%;border:4px solid var(--newCommunityTheme-bodyTextAlpha20);border-left-color:var(--newCommunityTheme-body);transform:translateZ(0);animation:ibDwUVR1CAykturOgqOS5 1.1s linear infinite}._3LwT7hgGcSjmJ7ng7drAuq,._3LwT7hgGcSjmJ7ng7drAuq:after{width:var(--sizePx);height:var(--sizePx)}._3LwT7hgGcSjmJ7ng7drAuq:after{border-radius:50%}._3LwT7hgGcSjmJ7ng7drAuq._2qr28EeyPvBWAsPKl-KuWN{margin:0 auto} Any doctor interested in giving an opinion on the case? Studies show it can help slow or reverse the process of hair loss. Brain Res Bull. This site needs JavaScript to work properly. 2012;97:306. Finasteride is available as a lower-cost generic. I was able to have 8 sexual encounters in 1 week with different people - I felt no PFS symptoms whatsoever My muscle mass and body fat composition is now normal, my semen thickened, Peyronies stabilized, penis pain subsided, testicular pain is rare cognitive issues are resolved, and overall I think I've bounced back almost entirely. Public Health. -. https://camas.github.io/reddit-search/#{%22author%22:%22mrgoodcat1990%22,%22resultSize%22:100,%22query%22:%22pssd%20numbness%22}, ._3K2ydhts9_ES4s9UpcXqBi{display:block;padding:0 16px;width:100%} I'm not a gym rat, I just make sure to walk 3-5 miles a day and do my best to watch what I eat (that's always been the case.) Fertil Steril. Firstly, hair loss doesn't just affect older people. However, minoxidil is used "off-label" for treating telogen effluvium, scarring alopecia and alopecia areata. Getting to the root cause of your hairloss would be the first thing to do as if you have an underlying medical condition, once thats treated, it could reverse the hairloss, so definately get a consultation with a physician to rule out anything treatable. I haven't introduced any other supplements or medications. Hcg I did 3000iu the first day then 250iu every other day for the four weeks. Palliative care frightens some people: Heres how it helps, Parents don't always realize that their teen is suicidal. Im on HCG now too though so who knows, maybe itll help too, Powered by Discourse, best viewed with JavaScript enabled, Video: "Is Post Finasteride Syndrome Real? This is to be expected because you are messing with a hormone (DHT) that is very important for sexual function. 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